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In the context of aging, senescent ECs show increased expression of FA transporters, such as CD36 and FABP, suggesting a metabolic shift from glycolysis to FA oxidation to support a proinflammatory phenotype [91]
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Cotadutide (medi0382), a dual receptor agonist with glucagon-like peptide-1 and glucagon activity, modulates hepatic glycogen and fat content
125 Notably, ELISA demonstrate that IDH1 level is also significantly elevated in the plasma of NSCLC patients, suggesting that it can be used as a potential plasma biomarker
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