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Individuals with T2DM or HIV have been shown to have decreased levels of IFN-gamma

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Antiproliferation assays demonstrate its potent inhibitory effects across multiple KRAS G12C -mutant cancer models

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The use of statins at higher concentrations than in the present study has been previously associated with varying effects on insulin secretion: simvastatin was shown to reduce, while pravastatin increased insulin secretion in response to glucose, with GLP-1 or exendin-4 exposure restoring secretory responses from statin-treated cells (48)