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In simple obesity (body mass index = 30.034.9 kg/m2), the annual probability of attaining normal weight was 1 in 210 for men and 1 in 124 for women , increasing to 1 in 1290 for men and 1 in 677 for women with morbid obesity (body mass index = 40.044.9 kg/m2)

255 miR-30 inhibition triggers Notch1 signaling, pro-inflammatory cytokine (TNF and CCL2) production, and M1 macrophage polarization, indicating that miR-30 manipulation could be a therapeutic approach for reducing obesity-induced inflammation

Redox-associated metabolic responses By the age of 12-mo, commensals anaerobes (e.g., Bifidobacterium, Bacteroides , Clostridium ) are colonized 1001000 times more frequently than aerobic bacteria due to a substantial increase in the populations of facultative bacteria throughout infancy (e.g., Enterobacteriacea e, Enteroccocus , Streptococcus ) 87

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Available from: Cai WF, Zhang C, Wu YQ, Zhuang G, Ye Z, Zhang CS, et al