What should I expect during dose escalation
The FXR agonists bind to the receptors and activate them and regulate target genes involved in the biological pathways
In contrast, extremely low frequency electromagnetic fields (ELF-EMFs, ferroptosis-promoting EMFs, operating at 50 Hz and with magnetic field density between 1 T and 1 mT 2%) act as potent ferroptosis promoters by triggering calcium-dependent oxidative stress
J Agric Food Chem 42: 3-20
Eur J Neurosci 11(9):31993214 Travaglione V, Peacock C, MacDougall J, McGovern K, Cushing J, Yu LC, Trudeau M, Palombella V, Adams J, Hierman J, Rhodes J (2008) A novel HH pathway inhibitor, IPI-926, delays recurrence post-chemotherapy in a primary human SCLC xenograft model Tremblay MR, Lescarbeau A, Grogan MJ, Tan E, Lin G, Austad BC, Yu LC, Behnke ML, Nair SJ, Hagel M, White K (2009) Discovery of a potent and orally active hedgehog pathway antagonist (IPI-926)