according to the latest meta-analysis including over 11 million patients, the rate for the world population is 1 : 313, but in patients with ischaemic heart disease the incidence is 10 times higher (1 : 31), with premature ischaemic heart disease 20 times (1 : 15), and in those with severe hypercholesterolaemia, 23 times higher (1 : 14) [276]
Bremholm L, Andersen UB, Hornum M, Hilsted L, Veedfald S, Hartmann B, et al
A 2013 review in Aging Cell showed that declining systemic IGF-1 correlates with reduced dermal collagen density and skin elasticity in adults over 60
In Vivo 38 , 160173 (2024)
Hair loss was recorded in 4.24 percent of patients taking tirzepatidethe ingredient in Mounjaro and Zepboundcompared with 3.33 percent taking semaglutide, which is sold as Ozempic and Wegovy