Artemisinin-based combination therapy (ACT), combining a fast-acting artemisinin derivative with a longer-acting partner drug, is the current recommended first-line treatment for uncomplicated malaria caused by Plasmodium falciparum 2
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Shungus subsequent findings, which included finding low levels of the main antioxidant in the brain (glutathione) in ME/CFS patients, suggested that neuroinflammation and oxidative stress are the key culprits in ME/CFS and/or FM Shungu believes an antioxidant poor environment allows an infection to trigger a free radical explosion which shuts down the blood vessels causing a hypoxic low oxygen environment in the brain
doi: 10.1177/19458924231157619
Animal and cell-culture studies point to three overlapping pathways: promotion of angiogenesis (new blood-vessel formation, linked to VEGF), support for collagen and tendon repair, and anti-inflammatory effects
