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It may take several minutes before the consistency will change to a paste

The clearance window can range from 5-7 weeks, depending on the individual, though it usually takes five weeks at the highest dose

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Interestingly, the paclitaxel-induced allodynia could be reduced by administering PEA through multiple routes, e.g., intrathecal, intraplantar and directly into the brain via intracerebroventricular injection, evidence that PEA can act on both the peripheral and central nervous system to achieve therapeutic efficacy

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