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Preclinical studies have shown that this peptide fragment can influence pathways associated with lipid metabolism and intracellular signalling without eliciting broad growth hormonemediated effects
Consistent with this, Syn 1103 transgenic mouse models exhibit compact aggregates in TH-positive dopaminergic neurons of the substantia nigra and show increased vulnerability due to enhanced Syn 1103 toxicity 54
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The redness stays
B-vitamin deficiencies are also associated with various adverse pregnancy outcomes and complications including anaemia (Reference Metz85Reference Finkelstein, Fothergill and Venkatramanan89) , early pregnancy loss (Reference Finkelstein, Fothergill and Venkatramanan89Reference Diao, Luo and Li91) , hypertension in pregnancy and preeclampsia (Reference Liu, Liu and Wang92Reference Duffy, McNulty and Ward94) , low birth weight and intrauterine growth restriction (Reference Relton, Pearce and Parker95)
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