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Moestrup, S

Patients with contraindicationsincluding personal or family history of medullary thyroid carcinoma, multiple endocrine neoplasia type 2, or severe gastrointestinal diseaseshould not use GLP-1 medications

Within the research community, Cagrilintide has drawn interest as a subject for studying amylin and calcitonin receptor signalling, energy homeostasis, and satiety pathways in pre-clinical and laboratory models including alongside GLP-1 receptor agonists

Carcinogenesis, Mutagenesis, Impairment of Fertility Long term studies in animals to evaluate carcinogenic potential have not been done

This is the central tension of training on a GLP-1 drug, and managing it well is the difference between losing fat while preserving muscle and losing both