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This premature skin damage associated with aging wrinkles delayed wound healing developing hidradenitis suppurativa developing psoriasis developing certain types of skin cancer Smoking Hair Theres also vasoconstriction DNA damage generation of free radicals hormonal effects Nails It may also affect your fingernails and toenails and increase the likelihood of fungal nail infections

A fairly short life granted but still

The authors acknowledge that the associations with risk factors are different across studies, which means that its not sensible to compare the different bars across years in Figure 1 above

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